The incident took place Sunday, with more than 100 attackers taking part in the overnight raids about 3 a.m., the Red Cross said.
The attacks took place in Adamawa state near the border with Cameroon. Four villages, including Suwa and Bukutto, were razed, according to witnesses, the organization said.
The attacks are believed to be related to a feud between local cattle herders and farmers. At least 2,000 people have fled the area in hopes of avoiding the violence.
There is an immediate need for food, shelter, and other necessities for those displaced by the violence, the Red Cross said.